Porous spun polymeric structures and method of making same

A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 mum to...

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Bibliographic Details
Main Authors CHIN YEM, DAO KINH-LUAN (LENNY) D, MOHAN KSHITIJ, ZHONG SHENG-PING (SAMUEL), VU LIEM
Format Patent
LanguageEnglish
Published 16.02.2010
Subjects
BRAIDING
COTTON-WOOL
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS,NON-WOVEN FABRICS
HUMAN NECESSITIES
HYGIENE
KNITTING
LACE-MAKING
MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARYMATERIAL
MEDICAL OR VETERINARY SCIENCE
NON-WOVEN FABRICS
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TEXTILES
TRANSPORTING
TRIMMINGS
WADDING
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Summary:A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 mum to about 250 mum, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.
Bibliography:Application Number: US20060496187