Substituted oxoazaheterocyclyl compounds

This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inh...

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Main Authors BURNS CHRISTOPHER J, NEUENSCHWANDER KENT W, HANNEY BARBARA A, PAULS HEINZ W, CONDON STEPHEN M, BECKER MICHAEL R, BOBKO MARK A, DAVIS RODERICK S, LAU WAN F, KARPINSKI JOSEPH M, SPADA ALFRED P, MORRIS ROBERT L, SABUCO JEAN-FRANCOIS, GALLAGHER TIMOTHY F, HE WEI, JIANG JOHN Z, LI AIWEN, MYERS MICHAEL R, POLI GREGORY B, EWING WILLIAM R, CHOI-SLEDESKI YONG MI, GRONEBERG ROBERT D
Format Patent
LanguageEnglish
Published 03.11.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.
Bibliography:Application Number: US20030628093