Pyridopyrimidinones

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.

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Main Authors HOELZEMANN GUENTER, SOLER RIERA MARTA, JONCZYK ALFRED, ADAN JAUME, MITJANS FRANCESC, ACKERMANN KARL-AUGUST, RAUTENBERG WILFRIED, STAEHLE WOLFGANG, CRASSIER HELENE, ROSELL-VIVES ELISABET
Format Patent
LanguageEnglish
Published 16.06.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.
AbstractList The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.
Author MITJANS FRANCESC
ACKERMANN KARL-AUGUST
ADAN JAUME
STAEHLE WOLFGANG
JONCZYK ALFRED
ROSELL-VIVES ELISABET
CRASSIER HELENE
SOLER RIERA MARTA
RAUTENBERG WILFRIED
HOELZEMANN GUENTER
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– fullname: MITJANS FRANCESC
– fullname: ACKERMANN KARL-AUGUST
– fullname: RAUTENBERG WILFRIED
– fullname: STAEHLE WOLFGANG
– fullname: CRASSIER HELENE
– fullname: ROSELL-VIVES ELISABET
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Snippet The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Pyridopyrimidinones
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