Pyridopyrimidinones

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.

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Bibliographic Details
Main Authors HOELZEMANN GUENTER, SOLER RIERA MARTA, JONCZYK ALFRED, ADAN JAUME, MITJANS FRANCESC, ACKERMANN KARL-AUGUST, RAUTENBERG WILFRIED, STAEHLE WOLFGANG, CRASSIER HELENE, ROSELL-VIVES ELISABET
Format Patent
LanguageEnglish
Published 16.06.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.
Bibliography:Application Number: US20040579222