Cell-specific and/or tumor-specific promoter retargeting of herpes gamma 34.5 gene expression
The present invention relates to herpes viral mutants and methods of using these viral mutants for selectively targeting tumor cells or other populations of target cells. The viral mutants of the invention are capable of selective targeting due to the use of tumor-specific and/or cell-specific promo...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
07.04.2009
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to herpes viral mutants and methods of using these viral mutants for selectively targeting tumor cells or other populations of target cells. The viral mutants of the invention are capable of selective targeting due to the use of tumor-specific and/or cell-specific promoters to drive expression of the herpes gamma34.5 gene. |
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Bibliography: | Application Number: US20050042189 |