Crystalline VAP-1 and uses thereof

The present invention relates to crystalline vascular adhesion protein-1 (VAP-1) and in particular to methods for the use of structural information of crystalline human VAP-1 for ligand and/or inhibitor identification, design and production, as well as screening assays for detection of same. The inv...

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Main Authors NYMALM-REJSTROEM YVONNE, VIITANEN LENITA, SOEDERHOLM ANNU, SMITH DAVID, KIDRON HEIDI, SALMINEN TIINA, PIHLAVISTO MARJO, PENTIKAEINEN OLLI, NYROENEN TOMMI, AIRENNE TOMI, JOHNSON MARK
Format Patent
LanguageEnglish
Published 03.03.2009
Subjects
ANALOGUE COMPUTERS
CALCULATING
CHEMISTRY
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:The present invention relates to crystalline vascular adhesion protein-1 (VAP-1) and in particular to methods for the use of structural information of crystalline human VAP-1 for ligand and/or inhibitor identification, design and production, as well as screening assays for detection of same. The invention further relates to inhibitors identified by the assays according to the present invention.
Bibliography:Application Number: US20040557188