Computer software to computer-design optimum oligo-nucleic acid sequence candidate from nucleic acid base sequences analyzed and method thereof

• Main Authors: ISHIKAWA MITSUYOSHI, AOKI YOSHIAKI
• Format: Patent
• Language: English
• Published: 28.11.2006
• Subjects: ANALOGUE COMPUTERS; CALCULATING; COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS; COMPUTING; COUNTING; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

A computer software program to design an optimum oligo-nucleic acid base sequence candidate from nucleic acid base sequences being analyzed using a computer, the program comprising: a first command to receive the specification of respective tolerated ranges of double-chain bond temperature, base sequence length and GC content, and to store the information on the priority order of respective items in the memory; a second command, while extending the partial sequence in the aforementioned nucleic acid base sequences being analyzed, to determine whether or not a sequence in each length falls within respective tolerated ranges based on the priority items received by the aforementioned first command, and if it does fall within the ranges, to output the partial sequence in the applicable length as an oligo-nucleic acid base sequence candidate; and a third command to display, based on the aforementioned priority order, the oligo-nucleic acid sequence candidate outputted by the aforementioned second command along with the values of respective items.