Glucocorticoid receptor ligands for the treatment of metabolic disorders

This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or d...

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Main Authors KYM PHILIP R, RICHARDS STEVEN J, VON GELDERN TOM W, BISHOP RICHARD D, JACOBSEN PEER B, LINK JAMES T, LAI CHUNQIU, TU NOAH, CINK RUSSELL DREW, GATES BRADLEY D, LEANNA MARVIN ROBERT, HAGBERG LARS T
Format Patent
LanguageEnglish
Published 28.11.2006
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
STEROIDS
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Summary:This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
Bibliography:Application Number: US20030460491