Methods of making amidino compounds useful as nitric oxide synthase inhibitors

Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.

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Bibliographic Details
Main Authors DURLEY RICHARD C, BERGMANIS ARIJA A, HANSEN, JR. DONALD W, SNYDER JEFFREY S, WEBBER RONALD KEITH, SCHARTMAN RICHARD R, AWASTHI ALOK K, MOORMANN ALAN E, TRIVEDI MAHIMA, FOK KAM F, TSYMBALOV SOFYA, TJOENG FOE SIONG, HICKORY BRIAN S, GANSER SCOTT S, MANNING PAMELA T, PITZELE BARNETT S, HAGEN TIMOTHY J, PROMO MICHELLE A, MAO MICHAEL, HALLINAN E. ANN, SCHOLTEN JEFFREY A, TOTH MIHALY V
Format Patent
LanguageEnglish
Published 05.09.2006
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.
Bibliography:Application Number: US20020321969