Therapeutic polypeptides, nucleic acids encoding same, and methods of use

• Main Authors: PEYMAN JOHN A, ANDERSON DAVID W, SMITHSON GLENNDA, BURGESS CATHERINE E, CASMAN STACIE J, RIEGER DANIEL K, SHIMKETS RICHARD A, BOLDOG FERENC L, GUO XIAOJIA SASHA, VOSS EDWARD Z, EDINGER SHLOMIT R, ALSOBROOK II JOHN P, MACDOUGALL JOHN R, ZHONG MEI, KHRAMTSOV NIKOLAI, GANGOLLI ESHA A, GORMAN LINDA, PATTURAJAN MEERA, SPYTEK KIMBERLY A, LEPLEY DENISE M, PENA CAROL E. A, VERNET CORINE A. M
• Format: Patent
• Language: English
• Published: 13.12.2005
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.