6-membered heterocyclic compounds useful for selective inhibition of the coagulation cascade

The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.

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Bibliographic Details
Main Authors NEUMANN WILLIAM L, RUEPPEL MELVIN L, CASE BRENDA, WEBBER RONALD K, LONG SCOTT, MOORMANN ALAN E, GARLAND DANNY J, PARLOW JOHN J, HAYES MICHAEL J, SNYDER JEFFERY S, SOUTH MICHAEL S, HUANG HORNGIH, TRUJILLO JOHN, JONES DARIN E, HUANG WEI, TOTH MIHALY V, SCHOLTEN JEFFREY A
Format Patent
LanguageEnglish
Published 29.11.2005
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Bibliography:Application Number: US20020263637