3-substituted oxindole beta-3 agonists

• Main Authors: SPINAZZE PATRICK GIANPIETRO, TRANKLE WILLIAM GEORGE, BASTIAN JOLIE ANNE, ROCCO VINCENT PATRICK, SALL DANIEL JON, HE JOHN XIAOQIANG, JESUDASON CYNTHIA DARSHINI, WERNER JOHN ARNOLD, STEVENS FREDDIE CRAIG, SCHOTTEN THEO, REUHTER GERD, FINLEY DON RICHARD, RATZ ANDREW MICHAEL
• Format: Patent
• Language: English
• Published: 28.06.2005
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TRAPPING

The present invention relates to a beta3 adrenergic receptor agonist of formula (I); or a pharmaceutical salt thereof; which is capable of increasing lipolysis and energy expenditure in cells and, therefore, is useful for treating Type 2 diabetes and/or obesity.