4''-substituted-9-deoxo-9a-aza-9a homoerythromycin a derivative

The invention relates to a method of preparing compounds of the formulaand to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions...

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Bibliographic Details
Main Authors LETAVIC MICHAEL ANTHONY, KANEKO TAKUSHI, CHENG HENGMIAO, YANG BINGWEI VERA, GLAZER EDWARD ALAN, BRONK BRIAN SCOTT
Format Patent
LanguageEnglish
Published 17.08.2004
Edition7
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:The invention relates to a method of preparing compounds of the formulaand to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial protozoa infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
Bibliography:Application Number: US20020273879