Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents

The invention concerns compounds of formula (I)wherein each of G , G and G is CH or N; m is 1 or 2; R includes hydrogen, halogeno and (1-4C)alkyl; M is a group of the formula: NR<2-L> -T R in which R and R together form a (1-4C)alkylene group, L includes (1-4C)alkylene, and T is CH or N; A may...

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Bibliographic Details
Main Authors PRESTON JOHN, MAYO COLETTE MARIE, FAULL ALAN WELLINGTON, STOCKER ANDREW
Format Patent
LanguageEnglish
Published 04.05.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention concerns compounds of formula (I)wherein each of G , G and G is CH or N; m is 1 or 2; R includes hydrogen, halogeno and (1-4C)alkyl; M is a group of the formula: NR<2-L> -T R in which R and R together form a (1-4C)alkylene group, L includes (1-4C)alkylene, and T is CH or N; A may be a direct link; M is a group of the formula: (T R )r-L -T R in which r is 0 or 1, each of T and T is CH or N, each of R and R is hydrogen or (1-4C)alkyl, or R and R together form a (1-4C)alkylene group, and L includes (1-4C)alkylene; M may be a direct link to X; X includes sulphonyl; and Q includes naphthyl and a heterocyclic moiety; or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use as antithrombotic or anticoagulant agents.
Bibliography:Application Number: US20010800745