Sodium ion-driven chloride /bi-carbonate exchanger

The present invention discloses DNAs comprising nucleotide sequences set forth as SEQ ID NO:1 or NO:3 encoding Na<+>-driven Cl-/HCO3- exchanger, proteins comprising amino acid sequences set forth as SEQ ID NO:2 or NO:4, and their homologous proteins comprising an amino acid sequence having del...

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Bibliographic Details
Main Authors SEINO SUSUMU, YANO HIDEKI, WANG CHANGZHENG
Format Patent
LanguageEnglish
Published 06.01.2004
Edition7
Subjects
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Summary:The present invention discloses DNAs comprising nucleotide sequences set forth as SEQ ID NO:1 or NO:3 encoding Na<+>-driven Cl-/HCO3- exchanger, proteins comprising amino acid sequences set forth as SEQ ID NO:2 or NO:4, and their homologous proteins comprising an amino acid sequence having deletion, substitution, addition or insertion amino acids, which proteins, when expressed in a cell, functions as Na<+>-driven Cl-/HCO3- exchanger, and cells in which the proteins exogenously expressed.
Bibliography:Application Number: US20010920804