Process for preparing chiral (s)-2,3-disubstituted-1-propylamine derivatives

A process for the preparation of chiral (S)-2,3-disubstituted-1-propylamine derivatives, in which a carbonyl group of (S) 3,4-disubstituted-1-butanecarbonyl derivatives is converted to an amine group, and the conversion reaction is performed through Curtius rearrangement or Hoffman rearrangement.

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Bibliographic Details
Main Authors LEE WON JANG, ROH KYOUNG ROK, LEE JUNG HWAN, KIM KYUNG-IL, HWANG DAE IL
Format Patent
LanguageEnglish
Published 09.07.2002
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process for the preparation of chiral (S)-2,3-disubstituted-1-propylamine derivatives, in which a carbonyl group of (S) 3,4-disubstituted-1-butanecarbonyl derivatives is converted to an amine group, and the conversion reaction is performed through Curtius rearrangement or Hoffman rearrangement.
Bibliography:Application Number: US20000673123