N-cyclopentyl modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I:(wherein R1, R3, R4, R5, R6, R7, R8, X, n, x and y are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.

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Bibliographic Details
Main Authors MACCOSS MALCOLM, OATES BRYAN, SHAH SHRENIK K, HILFIKER KERRY A, CHAPMAN KEVIN T, LOEBACH JENNIFER L, SHEN DONG-MING, GUTHIKONDA RAVI N, MILLS SANDER G, FINKE PAUL E, KIM DOOSEOP
Format Patent
LanguageEnglish
Published 19.03.2002
Edition7
Subjects
CHEMISTRY
CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Summary:The present invention is directed to compounds of the formula I:(wherein R1, R3, R4, R5, R6, R7, R8, X, n, x and y are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
Bibliography:Application Number: US20000590750