Inhibitors or bone reabsorption and antagonists of vitronectin receptors

Novel inhibitors of bone reabsorption and antagonists of vitronectin receptorsThe present invention relates to 5-membered ring heterocycles of the formula I,in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as medicaments.The novel compou...

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Main Authors KNOLLE JOCHEN, STILZ HANS ULRICH, GADEK TOM, MCDOWELL ROBERT, GOURVEST JEAN-FRANCOIS, CARNIATO DENIS, WEHNER VOLKMAR
Format Patent
LanguageEnglish
Published 17.04.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel inhibitors of bone reabsorption and antagonists of vitronectin receptorsThe present invention relates to 5-membered ring heterocycles of the formula I,in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as medicaments.The novel compounds are used as vitronectin receptor antagonists and as inhibitors of bone reabsorption.
Bibliography:Application Number: US19970821253