Microspheres, process for their preparation and their use

Biocompatible microspheres containing one or more active principals, a biodegradable and biocompatible polymer and a surface-active agent which is also biodegradable and biocompatible, contain less than 10 ppm of heavy metals. These microspheres are prepared by providing a solution of the polymer an...

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Bibliographic Details
Main Authors VERRECHIA; THIERRY, SPENLEHAUER; GILLES, VEILLARD; MICHEL
Format Patent
LanguageEnglish
Published 19.09.2000
Edition7
Subjects
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Summary:Biocompatible microspheres containing one or more active principals, a biodegradable and biocompatible polymer and a surface-active agent which is also biodegradable and biocompatible, contain less than 10 ppm of heavy metals. These microspheres are prepared by providing a solution of the polymer and of the active principal in a water-immiscible solvent which is more volatile than water and mixing with an aqueous solution of the surface-active agent, followed by evaporation of the solvent.
Bibliography:Application Number: US19950455604