1- Methylcarbapenem derivatives

A 1-methylcarbapenem compound represented by the following formula (I): wherein R1 represents hydrogen or C1-C4 alkyl; R2 represents hydrogen or an ester residue; and A represents a group of the formula (A1) wherein n is 0, 1 or 2, P is 0, 1 or 2, R3 is hydrogen or C1-C4 alkyl and R4 is a group (Q2)...

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Main Authors KOJIMA; KATSUHIKO, ISHIKAWA; KATSUYA, YASUDA; HIROSHI, SHIMOJI; YASUO, OHYA; SATOSHI, UTSUI; YUKIO, KAWAMOTO; ISAO
Format Patent
LanguageEnglish
Published 18.07.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A 1-methylcarbapenem compound represented by the following formula (I): wherein R1 represents hydrogen or C1-C4 alkyl; R2 represents hydrogen or an ester residue; and A represents a group of the formula (A1) wherein n is 0, 1 or 2, P is 0, 1 or 2, R3 is hydrogen or C1-C4 alkyl and R4 is a group (Q2) wherein B is phenylene, phenylene(C1-C3)alkyl, cyclohexylene, cyclohexylene(C1-C3)alkyl or C1-C5 alkylene, R7 is hydrogen or C1-C4 alkyl, and R14 is a group -C(=NH)R8, wherein R8 is hydrogen or C1-C4 alkyl or a group -NR9R10, wherein R9 and R10 are the same or different and are hydrogen or C1-C4 alkyl; or a pharmacologically acceptable salt thereof.
Bibliography:Application Number: US19980095925