Microgels

PCT No. PCT/GB96/00863 Sec. 371 Date Dec. 11, 1997 Sec. 102(e) Date Dec. 11, 1997 PCT Filed Apr. 4, 1996 PCT Pub. No. WO96/31551 PCT Pub. Date Oct. 10, 1996A microgel is produced by a two-stage process wherein the monomers are first polymerized in the absence of solvent for a controlled period, and...

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Bibliographic Details
Main Authors GRAHAM; NEIL BONNETTE, MAO; JIANWEN
Format Patent
LanguageEnglish
Published 30.11.1999
Edition6
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:PCT No. PCT/GB96/00863 Sec. 371 Date Dec. 11, 1997 Sec. 102(e) Date Dec. 11, 1997 PCT Filed Apr. 4, 1996 PCT Pub. No. WO96/31551 PCT Pub. Date Oct. 10, 1996A microgel is produced by a two-stage process wherein the monomers are first polymerized in the absence of solvent for a controlled period, and in a second stage solvent is added and polymerization is completed. The polymer is preferably a polyurethane formed from a polyalkylene glycol, a triol and a diisocyanate. The molecular weight is typically 100,000 to 200,000. The microgels form granules which may be compressed into solid form. Such solid forms containing an active agent, such as a protein, are useful as sustained delivery devices.
Bibliography:Application Number: US19970930652