Selective dehalogenation process

PCT No. PCT/JP94/01280 Sec. 371 Date Feb. 1, 1996 Sec. 102(e) Date Feb. 1, 1996 PCT Filed Aug. 3, 1994 PCT Pub. No. WO95/04712 PCT Pub. Date Feb. 16, 1995A compound represented by the following formula (1) or (3): (1) (3) is subjected to a catalytic hydrogenolysis reaction in the presence of a base...

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Main Authors KAWANISHI; HIROFUMI, IKEYA; TAKANOBU, YUKIMOTO; YUSUKE, EBATA; TSUTOMU, AKIBA; TOSHIFUMI, KAMIHARA; SHINJI
Format Patent
LanguageEnglish
Published 14.07.1998
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:PCT No. PCT/JP94/01280 Sec. 371 Date Feb. 1, 1996 Sec. 102(e) Date Feb. 1, 1996 PCT Filed Aug. 3, 1994 PCT Pub. No. WO95/04712 PCT Pub. Date Feb. 16, 1995A compound represented by the following formula (1) or (3): (1) (3) is subjected to a catalytic hydrogenolysis reaction in the presence of a base and thus a compound represented by the following formula (2): (2) wherein R represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms and X represents a chlorine atom or a bromine atom; is easily produced. This compound is usable as an intermediate for the preparation of drugs.
Bibliography:Application Number: US19960592402