Isosorbide dinitrate-containing patch using a mixed adhesive

PCT No. PCT/JP95/00318 Sec. 371 Date Aug. 28, 1996 Sec. 102(e) Date Aug. 28, 1996 PCT Filed Feb. 28, 1995 PCT Pub. No. WO95/22970 PCT Pub. Date Aug. 31, 1995The present invention provides an ISDN-containing patch that causes minimal occurrence of skin rash and has excellent percutaneous absorption a...

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Bibliographic Details
Main Authors FUJII; TAKAO, FURUYA; MINORU, OHE; MICHISUKE, IWATA; MAKOTO
Format Patent
LanguageEnglish
Published 09.06.1998
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:PCT No. PCT/JP95/00318 Sec. 371 Date Aug. 28, 1996 Sec. 102(e) Date Aug. 28, 1996 PCT Filed Feb. 28, 1995 PCT Pub. No. WO95/22970 PCT Pub. Date Aug. 31, 1995The present invention provides an ISDN-containing patch that causes minimal occurrence of skin rash and has excellent percutaneous absorption and adhesive strength. The present invention discloses an isorbide dinitrate-containing patch comprising: an adhesive layer formed on a flexible support, wherein said layer comprises an adhesive composition containing adhesive and isosorbide dinitrate, the adhesive being composed of silicone-based adhesive (A) and polyvinyl acetate-based adhesive (B), their weight ratio being A:B=85:15 to 15:85, and the weight ratio of isosorbide dinitrate (C) to the adhesives (A+B) being (A+B):C=90:10 to 60:40.
Bibliography:Application Number: US19960700418