Adenovirus vectors for gene therapy
The present invention relates to novel adenovirus vectors for use in gene therapy which are designed to prevent the generation of replication-competent adenovirus (RCA) during in vitro propagation and clinical use. The invention also provides methods for the production of the novel virus vectors. Th...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
13.01.1998
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to novel adenovirus vectors for use in gene therapy which are designed to prevent the generation of replication-competent adenovirus (RCA) during in vitro propagation and clinical use. The invention also provides methods for the production of the novel virus vectors. These vectors maximize safety for clinical applications in which adenovirus vectors are used to transfer genes into recipient cells for gene therapy. |
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Bibliography: | Application Number: US19950409874 |