Aplha-substituted-3-benzyl-benzofurans

This invention relates to the fields of pharmaceutical and organic chemistry and provides novel 3-benzyl-benzofurans which are alpha -substituted with ether, thioether, amino, hydrazino, cyano or halo that are useful for the treatment of the various medical indications associated with post-menopausa...

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Bibliographic Details
Main Author MUEHL; BRIAN S
Format Patent
LanguageEnglish
Published 06.01.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to the fields of pharmaceutical and organic chemistry and provides novel 3-benzyl-benzofurans which are alpha -substituted with ether, thioether, amino, hydrazino, cyano or halo that are useful for the treatment of the various medical indications associated with post-menopausal syndrome, as well as estrogen dependent diseases including cancer of the breast, uterus and cervix. The present invention further relates to intermediate compounds and processes useful for preparing the pharmaceutically active compounds of the present invention, and pharmaceutical compositions.
Bibliography:Application Number: US19950536313