Process for the preparation of substituted 2-fluoro-pyrimidines

Unsubstituted or substituted 2-fluoro-pyrimidines can be prepared by reaction of the underlying 2-amino-pyrimidines with diazotization agents, mixtures of HF and H2O containing 30-70% by weight of HF, based on the total of HF and H2O, serving as reaction medium. The reaction medium can also contain...

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Bibliographic Details
Main Authors KLAUSENER; ALEXANDER, STEFFAN; GUIDO, WOLTERS; ERICH
Format Patent
LanguageEnglish
Published 28.10.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Unsubstituted or substituted 2-fluoro-pyrimidines can be prepared by reaction of the underlying 2-amino-pyrimidines with diazotization agents, mixtures of HF and H2O containing 30-70% by weight of HF, based on the total of HF and H2O, serving as reaction medium. The reaction medium can also contain diluents and/or inorganic salts, preferably fluorides.
Bibliography:Application Number: US19960643214