Quinolone- and naphthyridonecarboxylic acid derivatives

Disclosed are new quinolone- and naphthyridonecarboxyclic acid derivatives of the formula: wherein T represents a radical of the formula: and the other radicals are as disclosed herein, for example, the compound 7-(3a-amino-1,2,3,7a-tetrahydro-isoindol-2-yl)-1-cyclopropyl-6-fluoro- 1,4-dihydro-8-met...

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Bibliographic Details
Main Authors BREMM; KLAUS-DIETER, ENDERMANN; RAINER, PETERSEN; UWE, SCHENKE; THOMAS
Format Patent
LanguageEnglish
Published 21.10.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are new quinolone- and naphthyridonecarboxyclic acid derivatives of the formula: wherein T represents a radical of the formula: and the other radicals are as disclosed herein, for example, the compound 7-(3a-amino-1,2,3,7a-tetrahydro-isoindol-2-yl)-1-cyclopropyl-6-fluoro- 1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxyclic acid, their salts, antibacterial compositions containing them, processes for their preparation, and methods of using them to combat bacterial infections. Disclosed also are intermediates useful in said processes of preparation. Disclosed are new quinolone- and naphthyridonecarboxyclic acid derivatives of the formula: dical of the formula: and the other radicals are as disclosed herein, for example, the compound 7-(3a-amino-1,2,3,7a-tetrahydro-isoindol-2-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxyclic acid, their salts, antibacterial compositions containing them, processes for their preparation, and methods of using them to combat bacterial infections. Disclosed also are intermediates useful in said processes of preparation.
Bibliography:Application Number: US19950534369