Cloning of the gene which codes for the pilinic subunit fim3 of Bordetella pertussis

A cloned DNA fragment of Bordetella pertussis including the gene which codes for the pilinic subunit fim3, vectors which contain it and microorganisms transformed by the vectors. The protein and peptides corresponding to at least one epitope of the gene which codes for the pilinic subunit fim3 are p...

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Bibliographic Details
Main Authors RIBOLI; BARBARA, GRANDI; GUIDO, CUZZONI; ANNA, PEDRONI; PAOLA, DE FERRA; FRANCESCA
Format Patent
LanguageEnglish
Published 11.06.1996
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:A cloned DNA fragment of Bordetella pertussis including the gene which codes for the pilinic subunit fim3, vectors which contain it and microorganisms transformed by the vectors. The protein and peptides corresponding to at least one epitope of the gene which codes for the pilinic subunit fim3 are particularly useful for the development of acellular anti-pertussis vaccines. In addition, a strain of Bordetella modified by a recombinant replication or genome-integration vector containing the cloned DNA fragment or the gene or a fraction thereof is particularly suitable for the development of a cellular anti-pertussis vaccine.
Bibliography:Application Number: US19930029952