Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines

Disclosed are (R)- and (S)-isomers of the compounds of the Formulas II and III with at least 95% optical purity (II) (III) wherein R1 and R2 are the same or different and represent a hydrogen atom, a lower alkyl, lower alkenyl or lower alkynyl group, a cycloalkyl group or a group (CH2)m Ph, wherein...

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Bibliographic Details
Main Authors RAEMSBY; STEN I, STROEM; PETER H. E, HOE; THOMAS, FEDERSEL; HANS-JUEGEN
Format Patent
LanguageEnglish
Published 21.11.1995
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed are (R)- and (S)-isomers of the compounds of the Formulas II and III with at least 95% optical purity (II) (III) wherein R1 and R2 are the same or different and represent a hydrogen atom, a lower alkyl, lower alkenyl or lower alkynyl group, a cycloalkyl group or a group (CH2)m Ph, wherein m is 0-3 and Ph is a substituted or unsubstituted phenyl group. These compounds are intermediates in the stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines.
Bibliography:Application Number: US19940203985