Fragments of lactoferrin having potent antimicrobial activity

• Main Authors: KAWASE; KOHZO, WAKABAYASHI; HIROYUKI, TAKASE; MITSUNORI, BELLAMY; WAYNE R, TOMITA; MAMORU, YAMAUCHI; KOHJI
• Format: Patent
• Language: English
• Published: 19.04.1994
• Edition: 5
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

An antimicrobial peptide containing at least the following amino acid sequence (a), (b), (c) or (d), an antimicrobial agent containing the said antimicrobial peptide as active components at a concentration of at least 5 ppm (weight), an antimicrobial composition the said antimicrobial peptide and a method for processing products which uses the antimicrobial agent containing the said antimicrobial peptide. (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) LYS-Cys*-Arg-Arg-Trp-Gln-Trp-Arg--Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys*-Val-: (b) (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) (* CHEMICAL STRUCTURE *) Lys-Cys*-Phe-Gln-Trp-Gln-Arg-Asn--Met-Arg-Lys-Val-Arg-Gly-Pro-Pro--Val-Ser-Cys*-Ile-:(d) (* CHEMICAL STRUCTURE *)