Megakaryocyte colony stimulating factor and process for its preparation
PCT No. PCT/JP89/00960 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 21, 1989 PCT Pub. No. WO90/03397 PCT Pub. Date Apr. 5, 1990.A novel megakaryocyte colony stimulating factor has been isolated from the supernatant of the culture obtained by cultivating a cell strain of...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English |
Published |
02.11.1993
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Edition | 5 |
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Abstract | PCT No. PCT/JP89/00960 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 21, 1989 PCT Pub. No. WO90/03397 PCT Pub. Date Apr. 5, 1990.A novel megakaryocyte colony stimulating factor has been isolated from the supernatant of the culture obtained by cultivating a cell strain of a human large cell lung cancer. When the factor is applied to human or murine bone-marrow cells in vitro, it forms a megakaryocyte colony. Also, the factor increases the number of platelets in peripheral blood in vivo. |
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AbstractList | PCT No. PCT/JP89/00960 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 21, 1989 PCT Pub. No. WO90/03397 PCT Pub. Date Apr. 5, 1990.A novel megakaryocyte colony stimulating factor has been isolated from the supernatant of the culture obtained by cultivating a cell strain of a human large cell lung cancer. When the factor is applied to human or murine bone-marrow cells in vitro, it forms a megakaryocyte colony. Also, the factor increases the number of platelets in peripheral blood in vivo. |
Author | NOMURA; TAKEO MATSUNAGA; KEITA HAMAGUCHI; HIROYUKI KURIYA; SHINICHIRO NOJIRI; CHUHEI MAKABE; OSAMU OGATA; KIYOYUKI NAGAOKA; KOZO |
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Snippet | PCT No. PCT/JP89/00960 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 21, 1989 PCT Pub. No. WO90/03397 PCT Pub. Date Apr. 5, 1990.A... |
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SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
Title | Megakaryocyte colony stimulating factor and process for its preparation |
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