Megakaryocyte colony stimulating factor and process for its preparation

PCT No. PCT/JP89/00960 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 21, 1989 PCT Pub. No. WO90/03397 PCT Pub. Date Apr. 5, 1990.A novel megakaryocyte colony stimulating factor has been isolated from the supernatant of the culture obtained by cultivating a cell strain of...

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Main Authors OGATA; KIYOYUKI, NOJIRI; CHUHEI, KURIYA; SHINICHIRO, MAKABE; OSAMU, HAMAGUCHI; HIROYUKI, NOMURA; TAKEO, MATSUNAGA; KEITA, NAGAOKA; KOZO
Format Patent
LanguageEnglish
Published 02.11.1993
Edition5
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:PCT No. PCT/JP89/00960 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 21, 1989 PCT Pub. No. WO90/03397 PCT Pub. Date Apr. 5, 1990.A novel megakaryocyte colony stimulating factor has been isolated from the supernatant of the culture obtained by cultivating a cell strain of a human large cell lung cancer. When the factor is applied to human or murine bone-marrow cells in vitro, it forms a megakaryocyte colony. Also, the factor increases the number of platelets in peripheral blood in vivo.
Bibliography:Application Number: US19910668493