Drug release controlling coating material for long acting formulations

A coating material for controlling drug release, useful for long acting formulations-e.g. for once-a-day administration, and to a long acting granular composition comprising a drug (especially one conventionally difficult to prepare in long acting form) coated with the coating material. This composi...

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Main Authors FUKUI; MUNEO, SUGIURA; HIROSHI, KAJIYAMA; ATSUSHI, YONEYA; SATORU, OHMURA; TADAYOSHI, HOSONO; TOSHIHARU
Format Patent
LanguageEnglish
Published 02.11.1993
Edition5
Subjects
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Summary:A coating material for controlling drug release, useful for long acting formulations-e.g. for once-a-day administration, and to a long acting granular composition comprising a drug (especially one conventionally difficult to prepare in long acting form) coated with the coating material. This composition may be mixed with other granular drug formulations. The drug-release controlling coating material comprising, in a specific ratio, one specific water-insoluble and low water-permeability polymers and two materials differing from each other in the pH-dependency of their solubility (pH-dependent polymer-materials).
Bibliography:Application Number: US19920885910