Pentapeptide having specific inhibiting effect on epidermal cell proliferation, the salts thereof, pharmaceutical compositions comprising the same and a process for the preparation of the pentapeptide and the pharmaceutical compositions

The present invention relates to novel pentapeptide of formula pAad-Glu-Asp-Ser-Gly-OH, wherein pAad represents the acyl group of pyro-alpha-aminoadipic acid, and salts thereof having specific inhibiting effect on epidermal cell proliferation, and pharmaceutical compositions comprising the same. The...

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Bibliographic Details
Main Authors KISFALUDY, DECEASED; LAJOS, SCHON; ISTVA, SZIRTES; TAMAS, BALAZS; ANDRAS
Format Patent
LanguageEnglish
Published 12.10.1993
Edition5
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel pentapeptide of formula pAad-Glu-Asp-Ser-Gly-OH, wherein pAad represents the acyl group of pyro-alpha-aminoadipic acid, and salts thereof having specific inhibiting effect on epidermal cell proliferation, and pharmaceutical compositions comprising the same. The invention also relates to a process for the preparation of both the pentapeptide and the pharmaceutical composition.
Bibliography:Application Number: US19910750330