PARTICULATE BIOLOGICALLY ACTIVE REAGENT CONTAINING POLYOXYALKYLENE SIDE CHAINS, ANALYTICAL ELEMENT AND METHODS FOR USE OF THE REAGENT

Biologically active reagents are prepared from particles of copolymers having polyoxyalkylene side chains, each side chain having a molecular weight of at least 88. The reagents are prepared by covalently attaching biologically active substances, for example antibodies, to the particles, directly or...

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Bibliographic Details
Main Authors OENICK; MARSHA B, SUTTON; RICHARD C
Format Patent
LanguageEnglish
Published 06.04.1993
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:Biologically active reagents are prepared from particles of copolymers having polyoxyalkylene side chains, each side chain having a molecular weight of at least 88. The reagents are prepared by covalently attaching biologically active substances, for example antibodies, to the particles, directly or indirectly through reactive groups on the particle surface. These reagents are used to advantage in analytical elements and methods for the detection of specific binding ligands (such as immunological species) and immunoassays, and in purification methods as affinity chromatography reagents. Adsorption of undesirable proteins on the particles of the reagents was considerably reduced because of the specific composition of the particles.
Bibliography:Application Number: US19900558272