SYNTHESIS OF PURINE SUBSTITUTED CYCLOPENTENE DERIVATIVES

This invention relates to new process for preparing certain optically active purine substituted cyclopentene derivatives and novel intermediates used in this process. In particular, the invention concerns the synthesis of the 1R-cis isomer of carbovir, (1R-cis)-amino-1,9-dihydro-9-[4-(hydroxymethyl)...

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Bibliographic Details
Main Authors PETERSON; MARK L, MOOK, JR.; ROBERT A, PARTRIDGE; JOHN J, LACKEY; JOHN W, VINCE; ROBERT
Format Patent
LanguageEnglish
Published 30.06.1992
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:This invention relates to new process for preparing certain optically active purine substituted cyclopentene derivatives and novel intermediates used in this process. In particular, the invention concerns the synthesis of the 1R-cis isomer of carbovir, (1R-cis)-amino-1,9-dihydro-9-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-6H -purin-6-one, an antiviral agent, and certain intermediates.
Bibliography:Application Number: US19900505809