Tetrahydronaphthalene and indane compounds useful for reversing the photo-damage in sun-exposed skin

The use of compounds of formula I as topical agents to combat the disorders of the skin produced by photodamage which disorders include: wrinkling, elastosis and premature aging is described. Compounds of formula I are I wherein n represents 1 or 2, Z represents-SR, wherein R represents lower-alkyl,...

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Bibliographic Details
Main Authors BRYCE; GRAEME F, SHAPIRO; STANLEY S
Format Patent
LanguageEnglish
Published 24.12.1991
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Summary:The use of compounds of formula I as topical agents to combat the disorders of the skin produced by photodamage which disorders include: wrinkling, elastosis and premature aging is described. Compounds of formula I are I wherein n represents 1 or 2, Z represents-SR, wherein R represents lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkoxy-lower-alkyl, lower-alkanoyl-lower-alkyl, hydroxy-lower-alkyl, halo-lower-alkyl, lower-carbalkoxy-lower alkyl, mono-lower-alkylamino, di-lower-alkylamino, mono-lower-alkylamido, or di-lower-alkylamido and pharmaceutically acceptable salts thereof.
Bibliography:Application Number: US19900520165