Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same

• Main Authors: MODAK; SHANTA M, FOX, JR.; CHARLES L, SAMPATH; LESTER A
• Format: Patent
• Language: English
• Published: 28.05.1991
• Subjects: ACCESSORIES; ADHESIVES; AGRICULTURE; ANIMAL HUSBANDRY; BANDAGES, DRESSINGS OR ABSORBENT PADS; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMICAL PAINT OR INK REMOVERS; CHEMISTRY; COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; CORRECTING FLUIDS; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DIAGNOSIS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; DYES; FILLING PASTES; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FISHING; FOMENTATION; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; IDENTIFICATION; INKS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC MACROMOLECULAR COMPOUNDS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; OUTERWEAR; PAINTS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; POLISHES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROSTHESES; PROTECTIVE GARMENTS; SURGERY; THEIR PREPARATION OR CHEMICAL WORKING-UP; TRAPPING; TREATMENT OR PROTECTION OF EYES OR EARS; USE OF MATERIALS THEREFOR; WEARING APPAREL; WOODSTAINS

A method of preparing an infection-resistant medical device comprising one or more matrix-forming polymers selected from the group consisting of biomedical polyurethane, biomedical silicones and biodegradable polymers, and antimicrobial agents, especially a synergistic combination of a silver salt and chlorhexidine (or its salts); also disclosed are medical devices having the synergistic composition therein or compositions thereon.