Pharmaceutical compounds
Compounds of the following formula have pharmaceutical properties: in which X is R'(HO)C=C(CN)-, R1(CO)-CH(CN)- or R1 and R2 are each hydrogen or C1-6 alkyl, R3, R4, R5 and R6 are each hydrogen, hydroxy, halogen, nitro, cyano, carboxy, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, halo-substituted C...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
08.01.1991
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Subjects | |
Online Access | Get full text |
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Summary: | Compounds of the following formula have pharmaceutical properties: in which X is R'(HO)C=C(CN)-, R1(CO)-CH(CN)- or R1 and R2 are each hydrogen or C1-6 alkyl, R3, R4, R5 and R6 are each hydrogen, hydroxy, halogen, nitro, cyano, carboxy, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, halo-substituted C1-4 alkyl, halo-substituted C1-4 alkoxy, halo-substituted C1-4 alkylthio, C2-5 alkoxycarbonyl, optionally substituted phenyl, optionally substituted phenoxy, R'R''N- where R' and R'' are each hydrogen or C1-4 alkyl or R'''CONH- where R''' is C1-4 alkyl, or a group of the formula -CR7R8R9 in which R7, R8 and R9 are each C1-6 alkyl, halo-substituted C1-6 alkyl or optionally substituted phenyl, or R7 and R8, together with the carbon atom to which they are attached, form a cycloalkyl group containing 3 to 7 carbon atoms, or R7, R8 and R9 together with the carbon atom to which they are attached, form a bicycloalkyl group containing 4 to 9 carbon atoms, and Y is a 5- or 6-membered heterocyclic ring excluding pyrazole; and salts thereof. |
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Bibliography: | Application Number: US19900464644 |