Transmembrane integrator sequences

Novel DNA constructions are provided, as well as their expression products, involving the use of transmembrane integrator sequences joined from one to two open reading frames and optionally a signal sequence, particularly at the N-terminus. The DNA constructs when used with membranal translation sys...

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Bibliographic Details
Main Authors YOST; CHARLES S, LINGAPPA; VISHWANATH R
Format Patent
LanguageEnglish
Published 08.01.1991
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Summary:Novel DNA constructions are provided, as well as their expression products, involving the use of transmembrane integrator sequences joined from one to two open reading frames and optionally a signal sequence, particularly at the N-terminus. The DNA constructs when used with membranal translation systems provide for translocation of the peptides into the membrane. Alternatively, a signal sequence may be introduced internal to an open reading frame, where the resulting translation product may be processed by a membrane to provide two peptides.
Bibliography:Application Number: US19860906809