4-phosphorus-2-phthalimidobutyrate intermediates

Phosphinylbutanoic acids, such as phosphinothricin, can be prepared by reacting racemic 4-halo-2-phthalimidobutyrates with a tricoordinate phosphorus compound represented by the formula: R1-P-(R2)2 wherein R1 is methyl or ethyl, and R2 is selected from the group consisting of alkoxy having from one...

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Bibliographic Details
Main Author LOGUSCH; EUGENE W
Format Patent
LanguageEnglish
Published 16.08.1988
Edition4
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:Phosphinylbutanoic acids, such as phosphinothricin, can be prepared by reacting racemic 4-halo-2-phthalimidobutyrates with a tricoordinate phosphorus compound represented by the formula: R1-P-(R2)2 wherein R1 is methyl or ethyl, and R2 is selected from the group consisting of alkoxy having from one to six carbon atoms, aryloxy, and trialkylsilyloxy groups having from one to twelve carbon atoms, to form an intermediate compound; and hydrolyzing the intermediate compound to form the phosphinylbutanoic acids.
Bibliography:Application Number: US19870060692