Process for producing an indoline
A process for producing an indoline of the formula: (I) wherein R1 is a hydrogen atom, a lower alkyl group, a lower alkoxy group, a nitro group or a hydroxyl group, R2 is a hydrogen atom, a lower alkoxy group or a nitro group, and R3 is a hydrogen atom, a lower alkyl group or a substituted lower alk...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
16.06.1987
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Summary: | A process for producing an indoline of the formula: (I) wherein R1 is a hydrogen atom, a lower alkyl group, a lower alkoxy group, a nitro group or a hydroxyl group, R2 is a hydrogen atom, a lower alkoxy group or a nitro group, and R3 is a hydrogen atom, a lower alkyl group or a substituted lower alkyl group, by a cyclization reaction of a 2-halogenophenethylamine of the formula: (II) wherein R1, R2 and R3 are as defined above, and X is a halogen atom, in the presence of a copper type catalyst and a dehydrohalogenating agent, characterized in that copper bis(8-hydroxyquinolinolate) is used as the copper type catalyst, and an alkali is used as the dehydrohalogenating agent. |
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Bibliography: | Application Number: US19850731393 |