Antibacterial benzo(chalcogeno)[4,3,2-cd]indazoles

Substituted 2H-[1]benzopyrano[4,3,2-cd]indazoles, 2H-[1]benzothiopyrano[4,3,2-cd]indazoles, and 2H-[1]benzoselenino[4,3,2-cd]indazoles have demonstrated pharmacological activity against a broad spectrum of Gram-positive and Gram-negative bacteria, yeasts, and fungi, as well as activity against the L...

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Bibliographic Details
Main Authors GREGOR; VLAD E, ELSLAGER; EDWARD F, SHOWALTER; HOWARD D. H, BERMAN; ELLEN M, SERCEL; ANTHONY D, WERBEL; LESLIE M, ORTWINE; DANIEL F, CAPPS; DAVID B, WORTH; DONALD F
Format Patent
LanguageEnglish
Published 05.08.1986
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Substituted 2H-[1]benzopyrano[4,3,2-cd]indazoles, 2H-[1]benzothiopyrano[4,3,2-cd]indazoles, and 2H-[1]benzoselenino[4,3,2-cd]indazoles have demonstrated pharmacological activity against a broad spectrum of Gram-positive and Gram-negative bacteria, yeasts, and fungi, as well as activity against the L1210 and P388 murine leukemia cells lines. Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating bacterial or fungal infections and of inhibiting the growth of neoplasms in mammals are also disclosed.
Bibliography:Application Number: US19850738195