Quinoline derivatives

Compounds of the formula: wherein X stands for an oxygen or sulphur atom, n stands for 1 or 2, R1 stands for a defined (3-4C)alkyl radical, a cyclopropyl radical, or a phenyl radical which may optionally bear a halogeno, (1-4C)alkyl or (1-4C)alkoxy substituent, and R2 stands for hydrogen or a (1-4C)...

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Bibliographic Details
Main Author LE COUNT; DAVID J
Format Patent
LanguageEnglish
Published 18.03.1986
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of the formula: wherein X stands for an oxygen or sulphur atom, n stands for 1 or 2, R1 stands for a defined (3-4C)alkyl radical, a cyclopropyl radical, or a phenyl radical which may optionally bear a halogeno, (1-4C)alkyl or (1-4C)alkoxy substituent, and R2 stands for hydrogen or a (1-4C)alkyl radical, and pharmaceutically-acceptable acid-addition salts thereof. Process for the manufacture of said compounds. Pharmaceutical compositions comprising one of said compounds and a pharmaceutical diluent or carrier. The compounds are peripherally selective 5-HT antagonists.
Bibliography:Application Number: US19840583035