Process for separating pharmaceutically active diindole alkaloids

A mixture of minor diindole alkaloids from Vinca-containing vinblastine and 4-deacetoxy-vinblastine vines, are separated by subjecting the mixture to a deacetylation to correct the vinblastine to deacetyl-vinblastine prior to chromatographic separation of said mixture in a single stage.

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Bibliographic Details
Main Authors JOVANOVICS, KAROLA, TAMAS, JOZSEF, LORINCZ, CSABA, SZOLLOSY, ARON, SZASZ, KALMAN, SUGAR, JANOS, ECKHARDT, SANDOR, RELLE, NEE SOMFAI ZSUZSA, DANCSI, LAJOS
Format Patent
LanguageEnglish
Published 24.06.1980
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A mixture of minor diindole alkaloids from Vinca-containing vinblastine and 4-deacetoxy-vinblastine vines, are separated by subjecting the mixture to a deacetylation to correct the vinblastine to deacetyl-vinblastine prior to chromatographic separation of said mixture in a single stage.
Bibliography:Application Number: US19780882418