Manufacture of epoxide using a microorganism

• Main Authors: TAOKA; AKIRA, SUZUKI; SHUZO, FURUHASHI; KEIZO
• Format: Patent
• Language: English
• Published: 15.08.1978
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HETEROCYCLIC COMPOUNDS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PROCESSES USING MICROORGANISMS; SPIRITS; TECHNICAL SUBJECTS COVERED BY FORMER USPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ARTCOLLECTIONS [XRACs] AND DIGESTS; VINEGAR; WINE

The production of epoxide from alpha -olefin or alpha , omega -diene using an epoxide producing microorganism that belongs to Nocardia genus, wherein said microorganism is cultured aerobically in a medium containing more than one straight-chain alpha -olefin and/or straight-chain, alpha , omega -diene chosen from alpha -olefins having 4 to 20 carbon atoms and alpha , omega -dienes having 4 to 20 carbon atoms, or cells obtained by culturing said microorganism in a medium containing assimilable carbon sources is allowed to react aerobically in a medium containing more than one alpha -olefin and/or alpha , omega -diene selected from said straight-chain alpha -olefins and/or alpha , omega -dienes, and produced alpha -epoxide or alpha , omega -diepoxide or a mixture of these is separated and harvested.