Substituted 4{40 -hydroxyphenyl guanidines and methods of using the same

Novel aromatic guanidine compounds having the formula: wherein: R1 is hydroxyl, methyl or hydroxymethyl and R2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical prepa...

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Bibliographic Details
Main Authors LIU; ROBERT CHUNG-HUAN, HUGHES; JOHN LAWRENCE
Format Patent
LanguageEnglish
Published 29.03.1977
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Novel aromatic guanidine compounds having the formula: wherein: R1 is hydroxyl, methyl or hydroxymethyl and R2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
Bibliography:Application Number: US19740518925