Preparation of thioethers of rifamycin S and rifamycin SV

New 3-thioethers of rifamycin SV are prepared by the reaction of rifamycin S with appropriate mercaptans. These thioethers of rifamycin SV are oxidized to yield the corresponding thioethers of rifamycin S. All these compounds exhibit significant antibiotic activity.

Saved in:
Bibliographic Details
Main Author CELMER; WALTER D
Format Patent
LanguageEnglish
Published 02.12.1975
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:New 3-thioethers of rifamycin SV are prepared by the reaction of rifamycin S with appropriate mercaptans. These thioethers of rifamycin SV are oxidized to yield the corresponding thioethers of rifamycin S. All these compounds exhibit significant antibiotic activity.
Bibliography:Application Number: US19740456721