PROCESS FOR THE PREPARATION OF 7-CHLORO-BENZODIAZEPINE DERIVATIVES

Process for the preparation of 7-Cl benzodiazepine derivatives comprised in the general formula WHEREIN R = H, CH3, R1 = H, OH, OCOCH3 and the ring B may be substituted or unsubstituted, characterized in that a benzodiazepine of the formula WHEREIN R, R1 and B have the above indicated meanings, is c...

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Bibliographic Details
Main Authors MAURI F,IT, ZIGGIOTTI A,CH, RIVA G,IT
Format Patent
LanguageEnglish
Published 03.12.1974
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Process for the preparation of 7-Cl benzodiazepine derivatives comprised in the general formula WHEREIN R = H, CH3, R1 = H, OH, OCOCH3 and the ring B may be substituted or unsubstituted, characterized in that a benzodiazepine of the formula WHEREIN R, R1 and B have the above indicated meanings, is chlorinated with elemental chlorine in the presence of nitrobenzene as the solvent.
Bibliography:Application Number: US19720230994