ANTIBIOTICS A28695A AND A28695B AND A PROCESS FOR PRODUCTION THEREOF

• Main Authors: HOEHN M,US, HAMILL R,US
• Format: Patent
• Language: English
• Published: 01.10.1974
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOUNDS OF UNKNOWN CONSTITUTION; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FODDER; FOODS OR FOODSTUFFS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

Method for the production of non-nitrogenous acid antibiotics, the antibiotic a28695 as defined above and the antibiotic a28695b as defined above, characterized by cultivating streptomyces albus nrrl 3883 in a nutrient culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under aerobic fermentation conditions submerged at a temperature of 26º to 40ºC until a substantial amount of the antibiotics a28695a and a28695b has been produced by said organism in said culture medium, recovering a mixture of said antibiotics from the culture medium and, if desired, separate the individual antibiotics a28695a and a28695b from the recovered antibiotic mixture. (Machine-translation by Google Translate, not legally binding)